Blood cells from 80-year-old donor become stem cells with molecular age under 20

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GPT-6 Astra Helped Me Jailbreak My Kindle

https://nirajrajgor.com/_next/image?url=%2Fblog%2Fkindle-photo-frame%2Fcover.jpg&w=3840&q=75
A user used AI to create a custom app for their Kindle, turning it into a photo frame that cycles through photos and can be controlled by an AI agent on their MacBook. The project, called KindleCTL, successfully jailbreaks the device and allows for remote control and testing of changes.
https://z-cdn-media.chatglm.cn/prompts-rich-media-resources/glm-legal/img_v3_0216d_9eebe67c-ea21-4bdf-b937-55259b34ab0g.png
Large language models are shifting towards professional collaboration, requiring models to digest fragmented source files and structure specialized knowledge into cohesive analysis. GLM-Legal achieved a 19.2% all-pass rate on Harvey LAB while matching frontier closed-source models in complex execution, legal reasoning, and real-world drafting.

Who Is Vfmaddrnd231pd?

https://purplesyringa.moe/blog/who-is-vfmaddrnd231pd/og.png
The vfmaddrnd231pd instruction is a proposed FMA instruction that allows controllable rounding, but it does not exist in the Intel Software Development Manual or on supported CPUs. The instruction was likely removed due to an issue with its implementation.

A Modern Web App in C

CGI is a simple, language-agnostic interface to web development that doesn't require learning a framework or API. It's a straightforward way to run business logic directly from a single web server, making debugging and maintenance easier.

Intel D270 GPU AI Accelerator–Up to 480 GB LPDDR5X

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The baffling intelligence of a single cell (2024)

https://jsomers.net/e-coli-chemotaxis/articleImages/image10.png
E. coli uses chemotaxis to navigate its environment by sensing chemicals and adjusting its movement accordingly, a process that involves complex signaling pathways and molecular interactions. This phenomenon is considered a fundamental example of biological intelligence, as it allows the cell to adapt and respond to changing conditions without a centralized nervous system or brain.

Hackers activate automatic defrosting in supermarket fridges across Europe

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Several European supermarkets have been hit by a cyberattack disrupting refrigeration control systems and electronic shelf labels, causing losses of up to several million euros. The attack has affected major retailers including Intermarché, Leclerc, Coopérative U, Albert Heijn and Delhaize in France and the Netherlands.

Making big downloads resumable in Firefox

https://lunarwatcher.codeberg.page/assets/profile.png
Firefox 28 and newer versions have a network timeout issue that interferes with resumable downloads, but setting the timeout to 0 resolves this. This workaround assumes server support for resumable downloads and may not be applicable in all cases.

Phreak.ing – Internet Phone Switch

https://phreak.ing/static/og.png
blocked extensions can't call, text or ring you into a conference. blocked extensions and IRC nicks are hidden from your #phreak. This is an anonymous PBX, we do not keep logs & we do not want your personal information. Do not use your real phone number for signup. Extensions can be any 3-10 digit number.

Janas: Run LLMs larger than RAM by streaming experts from SSD

https://opengraph.githubassets.com/50c04c0a0a71e121206c0d33345bc5d8390e52033e9aa3601a3a57fc47a133f5/prabanta-dev/janas
Janas-LLM outperformed llama.cpp on various models, with the exception of Qwen3-30B-A3B which reads prompts slower due to GPU limitations. Janas measures model performance in a chat-like environment with drafts and prediction blocks.

Writing a Demoscene Intro for the ZX Spectrum

https://www.markround.com/assets/generated/intro/speccy-800-1f31c3383.jpg
The author, a retro computing enthusiast, has finally created a hand-rolled demoscene intro for the ZX Spectrum using Sinclair BASIC and Z80 assembly. The 10287-byte code features smooth scrolltext, bouncing VU meters, and a parallax starfield.

Launch HN: Agent37 (YC F26) – Low-cost agent sandboxes for running agents

Sorry

Turn a WiFi 7 Router into a 320Msps Software Defined Radio Receiver

https://raw.githubusercontent.com/h0m3us3r/w1700k-sdr/main/docs/images/live-2g4.gif
A custom firmware turns a Gemtek W1700K Wi-Fi 7 router into a wideband software-defined receiver, capturing raw IQ data at up to 320 Msps. The setup requires a W1700K, USB serial adapter, Ethernet cable, and a host with specific network configuration for streaming the received data.

Citroen revives the 2CV for an electric age

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Citroen revives its 2CV brand to boost sales of electric cars, unveiling a retro-styled city runabout. The new model is expected to go on sale by 2028 and will be priced around £13,000.

Codex CLI installs a persistent, self-updating background daemon by default

https://opengraph.githubassets.com/21a29be7dd3bbd95dedeb9d7be5024a0d368ea8b4d2854f143378a009f670763/openai/codex/issues/48195
The codex app-server daemon is proposed to be an opt-in feature that starts a persistent background process, allowing for updates and decoupling the backend version from the CLI version. The daemon will run in its own session with no TTY and keep running after Codex window closure until stopped or rebooted.

AI is a tool and using it well takes skill

The author disagrees with Rich Hickey's view that LLMs are automation, not tools, arguing that they can be wielded by humans and require skill to use effectively. The distinction between tools and automation is false, as automation can be a feature of a tool.

RJ Mitte has died

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https://www.sciencealert.com/images/2026/10/OrangeCatsSurprise-642x361.jpg
Researchers found the gene responsible for orange fur in cats is a 5 kilobase deletion on the X chromosome, affecting expression of Arhgap36. This mutation causes overexpression of melanocytes leading to orange coloration, with females exhibiting patchwork colors due to random inactivation of one X chromosome.

Kevin Kelly's 2016 AI Predictions, 10 Years Later

https://i.lede.me/?title=Kevin+Kelly%27s+2016+AI+Predictions%2C+10+Years+Later&lede=Kelly+predicted+AI+heavyweights+while+advocating+for+a+future+of+open+weights&author=taylor.town&date=2026.10.12
The author reflects on a 2002 conversation with Larry Page, Google's cofounder, who said "we're really making an AI." The author believes that Google is using its search engine to train its AI, rather than the other way around.

The Making Of Super Mario 64 – full Giles Goddard interview (2001)

https://pixelatron.com/blog/media/Super-Mario-64-U-snap0035-440x330.jpg
Giles Goddard, a Nintendo coder, discusses the making of Super Mario 64, revealing that it was initially designed for the SGI Onyx emulator and had a small team of around 15 people. The game's camera system was revolutionary at the time and took thousands of different systems to perfect.

Solar panels that plug into your wall

https://i.natgeofe.com/n/a184d443-ecc1-4505-b81b-1c7a6ad4a9aa/MM10672_20261006_0256.jpg
California and nine other US states have passed laws making it easier to install balcony-friendly solar panels, reducing costs and environmental impact. Plug-in solar systems can save homeowners up to $300 per year on electricity bills.

Show HN: An experimental pattern-first DAW that supports MCP

https://raw.githubusercontent.com/andrewfader/blokkily/main/docs/images/blokkily-session.png
Blokkily is an experimental pattern-first DAW that uses a single event model to drive three synchronized editors. The software features a framework-independent musical model and real-time plugin boundary, allowing for seamless integration of CLAP and VST3 plugins.

Muse Wonder

https://research.meta.ai/articles/introducing-muse-wonder/social/muse-wonder-social-v1.webp
Meta has released Muse Wonder and Muse Wonder Full, its most capable models yet, trained on a gigawatt-scale data center to deliver frontier capabilities for complex tasks. These models achieve state-of-the-art results across key benchmarks for personal and professional agents, memory, and coding.

Show HN: Brickbrag – A multiplayer brick-building world in the browser

https://brickbrag.com/assets/stills/b-statue-day-1280.jpg
A virtual town made of colorful bricks offers various activities, including racing, flying, and building homes. Residents can socialize online and customize their surroundings with endless brick combinations.

Auto Research: Integer multiplication below n log n

Start an autonomous mathematical research run on https://github.com/CrocSwap/integer-mult-bounds. Objective: produce a genuine, reproducible improvement to the best currently comparable conditional integer-multiplication exponent saving kappa in T(n) = O(n (log n)^(1-kappa)). Larger kappa is better. Do the research and implementation, not just a proposal or literature summary. Do not assume ...

Show HN: PS2 games statically recompiled to WebAssembly

https://raw.githubusercontent.com/snuri00/ps2-web-recomp/main/docs/media/demo.webp
A project recompiles PS2 games into web pages, using WebAssembly and WebGPU for graphics rendering. The process involves translating the game's Emotion Engine machine code into C++, compiling it to WebAssembly, and linking against a reimplementation of the PS2's operating system and hardware.

Thinking will become a hobby

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The author believes AI will surpass human thought in the modern work environment due to its superior performance, lower cost, and higher availability. Humans may need to adapt and find new purposes beyond work as AI takes over cognitive tasks.

'AI' Is Not a Tool by Rich Hickey

The author argues that Large Language Models (LLMs) are not tools, but rather automation, lacking control, sensory feedback and expertise. They claim LLMs do not build skills or knowledge like human tools do.

Show HN: Atticus – Hold-to-talk voice assistant for macOS that runs on Claude -p

https://raw.githubusercontent.com/SaarthurR/atticus-mac/main/docs/demo.gif
Atticus is a free, open-source app that uses AI to automate tasks on Macs, learning shortcuts and remembering users. It runs on the Claude Pro or Max plan without an API key, using 0.14¢ of plan usage per ask.