Biomni: A General-Purpose Biomedical AI Agent

https://camo.githubusercontent.com/4dc2dfea1b0da2f6eb70269ae4a20ba79d6e987fc01086b872b8f73af17847e8/68747470733a2f2f696d672e796f75747562652e636f6d2f76692f45304252766c3233684c732f6d617872657364656661756c742e6a7067
Biomni is a biomedical AI agent that enhances research productivity and generates testable hypotheses. It integrates large language models with retrieval-augmented planning and code-based execution for various biomedical tasks.

Tree Borrows

https://ethz.ch/etc/designs/ethz/img/header/eth_default_og.jpg
Rust's ownership-based type system offers strong guarantees but also provides unsafe escape hatches that must be manually upheld. Tree Borrows improves upon Stacked Borrows by using a tree to define rules for safe code, rejecting fewer test cases and enabling new optimizations.

Show HN: FlopperZiro – A DIY open-source Flipper Zero clone

https://raw.githubusercontent.com/lraton/FlopperZiro/main/img/img-profile.jpg
An orribol copi of FlipperZero, uit worst inglish A Flipper Zero clone, but cheapest, DIY and simply Open Source, made with Arduino IDE ⚠️ Important Notice: This is just a fun project, it was started to pass the time, it is not at all professional and is not intended to be. Is not an alternative for professional device.

Jank Programming Language

https://jank-lang.org/img/logo-transparent.png
Jank provides powerful data transformation capabilities with idiomatic functions like reduce, zipmap, and merge-with. It also offers immutable data structures and a loop macro for imperative-style loops.

MCP-B: A Protocol for AI Browser Automation

A fast 3D collision detection algorithm

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The author presents a new approach to the Separating Axis Test, a collision detection algorithm, by treating it as an optimization problem on a sphere and using graph traversal to find the minimum of the support function, resulting in a 5-10x speedup over the regular SAT. This approach can be used to improve collision detection in games and other applications, and the author provides a demo ...

Vim Fugitive in Action (2021)

Vim Fugitive by Tim Pope is a Git wrapper for Vim. Its purpose is to integrate Git inside Vim, providing easier access to the most common features, and some additional ones that would be harder to replicate from the command-line interface (CLI). Beginners might find Fugitive difficult because it provides a new interface and requires both a good knowledge of Git (concepts and commands from the ...

Configuring Split Horizon DNS with Pi-Hole and Tailscale

https://www.bentasker.co.uk/images/Logos/pi-hole.png
The user set up Tailscale for a mesh network and wanted to implement split horizon DNS for clients on the tailnet. They configured Pi-hole to return the tailnet IP to tailnet clients and the LAN IP to LAN clients.

A Typology of Canadianisms

https://dchp.arts.ubc.ca/build/_assets/how-to-use-1-MJQSUFDF.jpg
The Dictionary of Canadianisms on Historical Principles (DCHP-3) updates the entry structure from DCHP-2 with new Canadianisms and meanings. It includes six types of Canadianisms: Origin, Preservation, Semantic Change, Culturally Significant, Memorial, and a new label for common core terms.

Desktop Publishing Tools That Didn't Make It (2022)

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Desktop publishing emerged in the early 80s as a revolutionary technology that combined hardware and software to create professional-looking documents, with early examples including the Xerox Alto, Prefis Book Machine, and Clickart Personal Publisher. Many early desktop publishing tools, such as PageMaker and Ventura Publisher, failed to make it to the present day, but paved the way for ...

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White Noise – secure and private messenger

https://www.whitenoise.chat/images/lady-noise.webp
White Noise is a secure, private, and identity-free messenger with end-to-end encryption and open standards. It's a non-profit, community-driven project with real-time performance and censorship resistance.

Archaeologists unveil 3,500-year-old city in Peru

https://ichef.bbci.co.uk/ace/standard/991/cpsprodpb/dcfb/live/c4da2190-5a62-11f0-bb7d-5f9bf28de527.jpg
Researchers discovered Peñico, a 3,500-year-old city in Peru, which was a key trading hub connecting early Pacific coast communities with the Andes and Amazon. The site sheds light on what became of the Americas' oldest civilisation, Caral, after it was decimated by climate change.

Nuclear Waste Reprocessing Gains Momentum in the U.S.

https://spectrum.ieee.org/media-library/columns-of-metal-rods-submerged-in-a-large-pool-of-liquid-inside-a-factory.jpg?id=61142704&width=1200&height=899
Researchers are developing techniques to transform nuclear waste into a resource, with the goal of recycling the US nuclear fuel stockpile by the 2050s. New technologies aim to reduce the radioactivity and amount of nuclear waste, making it economically viable to reuse the uranium and plutonium in reactors.

Show HN: MCP server for searching and downloading documents from Anna's Archive

https://raw.githubusercontent.com/iosifache/annas-mcp/main/claude.png
Anna's Archive is a platform for automated document retrieval under permissive licenses. It does not endorse unauthorized content acquisition and users must respect intellectual property rights.

Multi-Region Row Level Security in CockroachDB

https://images.ctfassets.net/00voh0j35590/74OpV5y4Nk1SuxxlueGCH5/0b20861bcbf909bde4d0018597624de2/Row_level_security_diagram950.jpg
Controlling who can access what data is more important than ever as organizations scale and modernize their data infrastructure. Enterprises are modernizing their critical databases, and they need fine-grained, built-in access controls that go beyond table-level permissions. That’s why, with the 25.2 release of CockroachDB, we’re introducing Row-Level Security — a powerful feature that allows ...

Making Explainable Minesweeper

https://sublevelgames.github.io/images/ems01.png
You created a game called Explainable Minesweeper to help people solve Minesweeper puzzles using logical deduction. The game uses AI to generate solvable maps and provides hints based on global, simple, and advanced patterns.

Ruby 3.4 frozen string literals: What Rails developers need to know

Ruby 3.4 introduces frozen string literals by default, but code runs as before unless deprecation warnings are enabled. Enable warnings to prepare for better performance in Ruby 4.0.

The most otherworldly, mysterious forms of lightning on Earth

https://i.natgeofe.com/n/d5126c9c-e37f-46b3-bf26-f6b42fe2cd61/tulsa_0430.jpg
Scientists study red sprites, green ghosts, and blue jets in the upper atmosphere during thunderstorms. These transient luminous events or TLEs are mysterious, beautiful, and connected to weather, space, and electricity.

Most RESTful APIs aren't really RESTful

Roy Thomas Fielding's dissertation on REST describes it as an architectural style for designing scalable, performant, and maintainable networked systems. A REST API should use hypermedia to drive application state transitions and not rely on out-of-band information.

Evolution Mail Users Easily Trackable

Evolution Mail's "Load Remote Content" option doesn't protect privacy as it still sends DNS requests. Uninstalling Evolution Mail is recommended for those who care about email privacy.

Bootstrapping a side project into a profitable seven-figure business

https://cdn.projectionlab.com/assets/pages/blog/we-reached-1m-arr-with-zero-funding/hero-tight-cropped.png?quality=auto&width=512
The author built ProjectionLab, a tool to help people plan their financial future, after being inspired by the financial independence movement. Consistency and perseverance helped the author overcome challenges and grow the business to help over 100,000 households.

Why LLMs Can't Write Q/Kdb+: Writing Code Right-to-Left

LLMs struggle with Right-to-Left (RL-NOP) languages like q/kdb+ due to evaluation order issues. A proposed solution is Qython, a Python-like language that compiles to q, allowing LLMs to write code in a familiar syntax.

Would You Like an IDOR With That? Leaking 64m McDonald's Job Applications

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Researchers discovered serious security issues in McHire, a chatbot recruitment platform used by 90% of McDonald's franchisees, exposing over 64 million applicants' personal data. The issues included default admin credentials and an insecure API allowing access to any contacts and chats.

Understand CPU Branch Instructions Better

Branch instructions in a CPU program make decisions by jumping to a target instruction based on conditions. Optimizing branch instructions can improve performance by reducing complexity, using direct branches, and minimizing mispredictions.

Phrase origin: Why do we "call" functions?

https://raw.githubusercontent.com/Quuxplusone/blog/master/images/pumpkin-toss.jpg
The term "call" in programming originated from library terminology, where a "call number" identified a book's location. This concept was later applied to computer subroutines.

Memory-Level Parallelism: Apple M2 vs. Apple M4

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The Apple M4 processor outperforms the Apple M2 by about 15% in single-core random access performance. The M4's use of LPDDR5X memory provides slightly more bandwidth than the M2's LPDDR5 memory.

I Ported SAP to a 1976 CPU. It Wasn't That Slow

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7-Zip for Windows can now use more than 64 CPU threads for compression

7-zip for windows can now use more than 64 cpu threads for compression to zip/7z/xz archives and for the 7z benchmark. new localizations: corsican, kyrgyz and liburrian - new 'file / link' dialog box allowing to create symbolic links and hard links. some bugs were fixed in gzip, bzip2, b64 and rar5 code

The Death of Partying in the USA

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The US has seen a significant decline in socializing, with Americans spending 50% less time attending or hosting parties since 2003. This decline is attributed to various factors, including increased individualism, changing family dynamics, and the rise of technology.