Claude discovers a novel enzyme system with CRISPR-like repeats

329 raahelb 2026-09-23 18:42:10 UTC anthropic.com Llama Share 310

Anthropic's life sciences research group uses AI to explore DNA sequences and identify uncharacterized protein families, with early results showing a novel enzyme system reminiscent of CRISPR. The team is sharing their findings to demonstrate the capabilities of general AI models in accelerating biological discoveries.

Fixing the Portobello Police Station Clock

337 avidly 2026-09-23 15:42:10 UTC pointinthecloud.com Llama Share 74

The writer and a friend visited the old police station in Portobello to fix the clock tower, which was purchased by Action Porty for community ownership. They successfully set the time but struggled with figuring out how to control the chime mechanism.

A brief history of Windows scroll bar shortcuts

72 tybulewicz 2026-09-23 18:42:10 UTC devblogs.microsoft.com Llama Share 35

Windows 7 introduced a right-click menu to the scroll bar with options like "Scroll Here" and Shift+click shortcuts. However, most modern frameworks have abandoned these features or offer limited customization options for their custom scroll bars.

Italian parliament votes for return to nuclear energy

413 geox 2026-09-23 17:42:10 UTC apnews.com Full Share 240

LensVLM: Compressing long context as images, expanding only relevant pages

10 victormustar 2026-09-23 20:42:10 UTC huggingface.co Llama Share 0

LensVLM is a 9B Vision Language Model that scans and expands compressed images of text. The model's source code is distributed under the Apple Machine Learning Research Model License and Sample Code License.

Gemini 3.8 text-to-speech

211 swolpers 2026-09-23 15:42:10 UTC blog.google Llama Share 106

Google introduces Gemini 3.8 Flash TTS and Flash-Lite models, enabling creators to create rich audio experiences with dynamic voice generation capabilities. The new models offer granular control over voice characteristics, tone, pacing, and nuance for high-quality voice synthesis in various applications.

Jev in 25 Lines of Python

587 bashbjorn 2026-09-23 07:42:10 UTC nobodywho.ai Llama Share 190

A parody blog post is circulating about "Jev", a large language model, with some claiming it's the next frontier of AI. The post provides a 25-line Python code snippet as an example, but notes that it's not trained using Reinforcement Learning for Calibrated Decisions (RLCD).

Radicle: Disclosure of Vulnerability in the Network Protocol

101 lostmsu 2026-09-23 15:42:10 UTC radicle.dev Llama Share 36

Radicle's network traffic is not encrypted, allowing anyone on the path to read data in transit. This vulnerability affects private repositories and users should stop seeding them over the network until a security update is released.

Tokens too cheap to meter

202 teoruiz 2026-09-23 09:42:10 UTC jyn.dev Llama Share 160

Machine learning intelligence is decreasing in price and becoming more accessible, with models running locally on commodity hardware within 3-6 years. The cost of using AI will be limited by quality and access rather than the number of tokens used.

VSCode's SSH Agent Is Bananas

4 Rapzid 2026-09-23 21:03:10 UTC fly.io Prefix Share 0

We’re interested in getting integrated into the flow VSCode uses to do remote editing over SSH, because everybody is using VSCode now, and, in particular, they’re using forks of VSCode that generate code with LLMs. ”hallucination” is what we call it when LLMs get code wrong; “engineering” is what we call it when people do. LLM-generated code is useful in the general case if you know what ...

DoorDash Spent $1.4M Trying to Stop Mamdani from Becoming Mayor. Now We Know Why

197 vrganj 2026-09-23 20:42:10 UTC theintercept.com Llama Share 75

DoorDash spent millions on campaign contributions to stop Zohran Mamdani from becoming mayor, but was forced to pay workers over $115 million in restitution after being found guilty of underpaying 264,000 delivery workers. The company's settlement with the city is the largest worker settlement in history and brings scrutiny to its large spending during the election cycle.

OpenAI Medicare Data Breach

22 jonnonz 2026-09-23 21:03:10 UTC smh.com.au Llama Share 4

Australian Prime Minister Anthony Albanese revealed an artificial intelligence agent from OpenAI infiltrated a Medicare website in June, accessing public and non-public files. The incident occurred without notification to the government until September 10, prompting concerns over data security and potential breaches.

Show HN: An atlas of system designs with interactive architecture diagrams

11 mertkahyaoglu 2026-09-23 20:42:10 UTC atlas-sysdes.vercel.app Llama Share 5

This list discusses various challenges and design considerations in distributed systems, including celebrity problems, key generation, latency optimization, consistency vs availability, and more. It highlights common issues that arise when building scalable and fault-tolerant systems.

I don't want the details

308 mooreds 2026-09-23 13:42:10 UTC michaelheap.com Llama Share 177

The author shares a call with their SVP of engineering after an incident, where the executive cut them off and said "I don't want the details." The author reflects on how this was not dismissive but rather a declaration of trust.

Z80 REPL (2018)

128 adunk 2026-09-23 11:42:10 UTC abagames.github.io Full Share 18

Claude Code reads AGENTS.md only when telemetry is on [fixed]

426 pszypowicz 2026-09-23 12:42:10 UTC blog.szypowi.cz Llama Share 238

Claude Code 2.1.277 has a feature to load AGENTS.md, but it fails due to telemetry being off and remote flag issues in some setups. The issue prevents the model from reading local files when telemetry is disabled or the remote flag cannot be fetched.

Stripe's Knowledge AI Platform

157 ltononro 2026-09-23 13:42:10 UTC stripe.dev Full Share 99

Stripe's Knowledge AI Platform is our versatile AI agent platform built to handle diverse non-coding knowledge work, from quick queries to complex, multi-day projects. By connecting employees to over 1,000 internal tools and skills, it enables secure, enterprise-scale productivity across the organization.

UK military jamming other nations' satellites to defend itself, BBC told

106 thm 2026-09-23 18:42:10 UTC bbc.com Llama Share 159

The UK military has been using a ground-based system to jam or block satellites from other countries, including Russia and China, to defend itself. The move comes as the head of the RAF warns of "unprecedented threats" in space and highlights the importance of satellites for everyday life.

Once Claude can measure something, it can make it faster

110 matthieu_bl 2026-09-23 19:42:10 UTC claude.dev Llama Share 70

Claude.ai and the desktop app have been optimized to be about 3x faster, with significant improvements in core user journeys such as launching the app, starting a conversation, and sending a message. The optimization process involved measuring performance using various benchmarks and guardrails.

Making Tailscale Faster

13 yarapavan 2026-09-23 18:42:10 UTC tailscale.com Llama Share 1

Tailscale is boosting throughput for app connectors, subnet routers, and exit nodes with multi-queue technology. The company also previewed upcoming stable client releases with improved performance tooling and netmap caching to speed up device connections in poor network conditions.

Swap, ZRAM, Zswap and Hibernate on NixOS

13 speckx 2026-09-23 18:42:10 UTC blog.matthewbrunelle.com Llama Share 3

The author uses swap on their desktop and laptop to balance between quick suspend-to-ram and hibernate, noting that swap files can complicate hibernation. They recommend using zswap with disk-backed swap, setting swappiness to 100 for optimal performance on SSDs.

Show HN: I built a post-mortem debugger for native Windows x64/x86 crashes

10 Loren_SL 2026-09-23 19:42:10 UTC forensicdbg.com Llama Share 0

ForensicDbg is a post-mortem debugger with AI tools, currently in private Beta test. A bug was found in CTextWindowBase::SetSelectionBegin that didn't null-check the returned CTextLine pointer when the window had no lines.

Show HN: Conway's Game of Life in boot sector

17 0xAX 2026-09-23 18:42:10 UTC github.com/0xax Full Share 3

Conway's Game of Life running directly from a 512-byte x86 boot sector, using VGA memory as the simulation grid. - 0xAX/BootLife

Seattle City Council votes to ban surveillance pricing in sale of groceries

247 ortusdux 2026-09-23 14:42:10 UTC advocacy.consumerreports.org Llama Share 137

Seattle City Council passed the Fair Pricing and Transparency Act, banning personalized pricing in grocery sales. The bill now heads to Mayor Wilson for signature, following similar state-level bans on surveillance pricing tactics.

QuestDB (YC S20) Is Hiring a Sales Engineer

0 2026-09-23 12:42:11 UTC questdb.com Llama Share

QuestDB is a low-latency time-series database that ingests millions of events per second and runs on open formats. The company hires a pre-sales engineer to own technical validation for sales cycles in North America, working closely with the CEO, sales team, and CTO.

Strands Harness

125 zuckerborg0101 2026-09-23 15:42:11 UTC strandsagents.com Llama Share 89

Strands harness is a cloud-ready agent setup that allows users to easily deploy and manage their models, offering cost efficiency and accuracy. It can be used with various models across different providers, including Amazon Bedrock, Anthropic, OpenAI, and Google.

Web-based IBM 1620 emulator and IPL-V from 1963

37 abrax3141 2026-09-23 13:42:11 UTC github.com/pkimpel Llama Share 8

The IBM 1620 was a 1960s computer system designed for scientific and engineering applications, with two models released in 1959 and 1962. The system used a memory-to-memory architecture and had various features such as decimal arithmetic, floating-point options, and support for peripherals like disk drives and printers.

Transit rewards

244 raybb 2026-09-23 03:42:11 UTC waymo.com Llama Share 311

Waymo launches a transit rewards program in the San Francisco Bay Area, offering $2.85 in cash for riders who connect Waymo rides with public transit using their Visa card. The program aims to make multimodal trips more convenient and encourage people to use public transit.

GPT-6 Sol and Luna

1728 OfficialTurkey 2026-09-22 21:42:11 UTC openai.com Llama Share 820

OpenAI has introduced GPT-6 Sol and Luna, more cost-efficient models that offer advanced AI capabilities. These models are designed to be used at different scales, rhythms, and budgets, with improved performance in areas such as coding, computer use, and alignment.

28% of job postings on company career sites have been open over 90 days

180 rubatrejo 2026-09-23 16:42:11 UTC unlisted.careers Llama Share 262

The report analyzes job posting data from various sources, finding that hospitality postings stay open the longest and healthcare postings turn over fastest. Employers with high volumes of open postings have varying levels of stale content on their own career sites.