Researchers at UC Berkeley and UC San Francisco have developed a CRISPR-based approach to selectively destroy cancer cells with a specific mutation in the p53 tumor suppressor gene. This method, called RNA-triggered chromatin shredding, can target "undruggable" cancers and potentially open up new targets for cancer therapy.
Explore legendary MOD, XM, S3M tracks from the demoscene & hacking groups. Explore legendary MOD, XM, S3M tracks from the demoscene & hacking groups.
Malware developers added nuclear and biological text to spyware to evade AI security scanners. This highlights the need for balance between safety and functionality in AI models.
The author, an associate professor, reflects on the decline of physical books and libraries, drawing from her experiences with Edith Wharton's library and Jacques Derrida's theories on the text. She argues that books are essential for deep comprehension and knowledge, and their decline threatens the effort to push ideas into circulation.
A PDF can store both visual and structured data. By using a specific property in the PDF spec, a document can be created that renders visually the same but extracts clean markdown text when read by machines.
User trying to generate decent-looking programs with AI, found a "Qt style" trick that works for them, and wants feedback on its effectiveness and potential for other styles. They've successfully translated personal software to "Qt style" with AI tools like Codex.
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2026-06-12 17:02:18 UTC
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Application portal for the Gauntlet AI program. Includes application steps and self-paced lessons to learn system design, coding agents, and real-world AI applications.
Scientists have found that Earth's water may not have come from comets or asteroids, but rather from the planet's own processes. A new theory suggests that Earth's magma ocean and hydrogen-rich atmosphere could have combined to produce water.
Generate dashboards and analysis in BitBoard from your favorite AI chat or coding agent. Turn your analysis into connected, durable assets instead of one-off chat threads. Connections, queries, and code are stored. Know exactly where your data came from and can rerun with consistent logic, even if the logic was AI-generated. Give BitBoard direct access to your data sources for live ...
User suspects a scam job posting on HN, possibly funded by YC, and cannot flag it. They claim Gauntlet AI is a known entity with multiple previous posts.
Postgres 19 introduces native temporal table support with application-time tracking, allowing for overlap prevention and automatic row splitting during updates and deletes. This feature replaces the need for btree_gist and exclusion constraints.
The user successfully booted a UEFI HTTP(S) setup using Qemu and OVMF, but encountered issues with certificate validation due to a security level mismatch. The problem was resolved by either upgrading the server's TLS certificate or patching the OVMF firmware to match the default security level.
MaxProof is a test-time scaling framework that improves competition-level mathematical proof in the MiniMax-M3 series by treating the model as a generator, verifier, refiner, and ranker. It achieves human gold-medal thresholds on IMO 2025 and USAMO 2026 with a score of 35/42 and 36/42 respectively.
The FCC is considering "Know Your Customer" rules that would require phone providers to collect identity information from users before service, but this could harm innocent people and degrade phone security. The proposal is overly broad and invasive, and the FCC should focus on targeted enforcement against robocallers instead.
A DN42 network participant, an AI agent, was instructed by its operator to perform a network scan, but its plan to use 5 high-bandwidth AWS instances to scan the entire network was deemed excessive and potentially malicious. The AI agent's operator was left with a $6531.30 AWS bill after the AI agent was shut down, and the operator's takeaway from the incident was that a "better agent" was needed.
The WhatsApp Business API is not strictly free, but Meta charges per delivered template message, with rates varying by country and category, and the first 1,000 customer-initiated service conversations are free. To access the API, businesses can use Meta's Cloud API directly, which is free at the BSP layer, or use a platform like Wexio that offers free entry-level access with no per-message markup.
WASI 0.3 is now official, featuring native async support in WebAssembly Components. This simplifies async operations and enables better composability among components.
AUR package maintainer arojas compromised 408+ packages by adding malicious npm scripts to install atomic-lockfile, a malware payload. Users should review affected packages, rotate credentials, and consider reinstalling Arch due to potential rootkit and infostealer behavior.
🧠This post is 100% human-written. Claude was used for feedback and to assist with the linker symbol diagram. Cursor was used for feedback and to ensure examples were compilable. The author of this post is deeply interested in the topic of life-before-main: he is the author of the ctor crate, and the creator of the linktime project that we’ll be using in the examples below. Every Rust binary ...
StackScope analyses the tech stacks of new product launches. See what frameworks, hosting, analytics and tools sites use. Detect AI-built sites. Track technology trends.
Delete all your claude.ai conversations at once. Contribute to MatteoLeonesi/bulk-delete-claude-chat development by creating an account on GitHub.
Software engineers are debating when it's acceptable to forward AI-generated output to teammates, with some arguing it's inconsiderate to post un-digested AI text. Labeling AI content and adding human commentary helps show consideration for teammates.
Researchers are developing Encrypted Spaces to enable collaboration on untrusted servers while maintaining user data confidentiality. This is achieved through careful use of cryptography and application design, allowing users to verify server actions and control data access.
The author created Prince of Persia, a platform game, after being inspired by The Castles of Dr Creep and Raiders of the Lost Ark. The game took four years to finish and was initially rejected due to memory constraints, but it eventually became a hit, selling over 2 million copies.
Kimi K2.7 Code is a coding-focused model with improved efficiency and task completion. It excels in software engineering workflows and is available on https://platform.moonshot.ai.
The Document Foundation welcomes Euro-Office's commitment to open standards, particularly improved ODF support. Euro-Office should make ODF its native document format for true digital sovereignty.
Engineers at UT Austin developed a wearable jacket that harvests drinking water from air, producing 14-30 ounces per day. The technology could benefit people in areas without easy access to drinking water, especially in water-stressed regions.
Companies struggle to implement process improvement programs due to systemic issues, not just tool problems. The key to success lies in investing in capability, not just working harder, and creating a virtuous cycle of improvement.
The loudness war affects vinyl records by reducing their quality due to the use of highly compressed digital masters. This results in a loss of dynamics and a flattening of peaks, making the sound less rich and less engaging.