Google DeepMind Releases AlphaGenome Atlas

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Scientists have developed the AlphaGenome Atlas, a database predicting effects of single nucleotide variants in the human genome. The Atlas helps researchers quickly prioritize promising research areas by providing an easy-to-use score for coding and non-coding regions.

DaVinci Resolve 21.1

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On the Navier–Stokes Millennium Prize Problem

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Researchers at OpenAI have developed a proof that the Navier-Stokes equations for fluid motion can develop a singularity in finite time, resolving one of the Millennium Prize Problems. The solution involves an internal model significantly more capable than GPT-6 Astra and demonstrates the potential for AI to advance research and technology benefiting humanity.

Benchmarking Qwen3.8 27B quantizations: 4-bit holds up, 1-bit collapses

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The author tested various GPU RAM requirements for running Qwen3.8 27B without sacrificing quality, finding that a 24 GB card like RTX 4090 can handle the full BF16 model with some context reduction.

OUI-1: world's first model for Generative UI

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A finetuned DiffusionGemma model, OUI-1, generates reliable user interfaces in openui-lang on consumer-grade hardware. It achieved a benchmark score of 71.7%, surpassing other models with similar parameters.

The Helicopter with Radioactive Blades

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The CH-53 Sea Stallion helicopter uses a simple mechanical system to detect rotor blade cracks, involving ionizing radiation from Strontium-90. This method has been effective for decades and is still used today in newer models with fiber optic sensors.

Show HN: LLM Attention Visualization

Connecting the Machines

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Herdr now allows users to control multiple machines from a single TUI, with each machine's sessions and agents available in the same interface. This feature enables seamless switching between machines without opening another client or worrying about SSH setup.

LG TVs caught spying even when offline or on standby

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LG smart TVs secretly log and upload data about owners even when offline, including location and Wi-Fi network details. This practice is part of Automatic Content Recognition (ACR) technology used by many smart TV manufacturers to identify what users watch.

I-have-ADHD: A skill to stop coding agents from burying the answer

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User wants to update jsonwebtoken API in auth.ts and run tests, also reviews claude plugin versions.

Show HN: Copperhead – Hardware as Fast as Software

https://copperhead.sh/_astro/pcb.CaISZw8z_2oKDw0.webp
Copperhead is an open-source AI platform for designing and verifying printed circuit boards. It helps hardware teams by automating the design process, ensuring consistency and accuracy.

The two Christian saints who are the Buddha

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The story of saints Barlaam and Josaphat originated from an Arabic version of the Buddhist tale, with similarities to the life of Gautama Buddha, and was later adopted by Christian churches. The shared themes across different faiths highlight a common human experience that transcends individual eras and places.

Y Combinator Early Access Network

The Early Access Network is an invite-only group of senior technology leaders who want to see what's coming before it's on anyone's shortlist. Four times a year, we put a hand-picked group of YC's...

ChatGPT Images 2.5

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OpenAI introduces ChatGPT Images 2.5, offering sharper details, faster generation, and better editing. New features like Sketch and templates enhance creative workflows for users and developers.

C*: Unifying Programming and Verification in C

https://arxiv.org/static/browse/0.3.4/images/arxiv-logo-fb.png
Researchers focus on formal verification of systems software due to its safety-critical nature. A new language, C*, integrates proof capabilities into C programming, enabling real-time verification and unifying implementation and proof code development.

AlphaGenome Atlas predictive map of every DNA letter change in the human genome

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Google has introduced AlphaGenome Atlas, a platform predicting the molecular impact of every possible single-letter DNA variant in the human genome. This comprehensive catalogue will help accelerate our understanding of biology and treat disease by providing researchers with an intuitive and free-to-use website portal.

ZX Spectrum: Experimenting with 1-Bit Sound

The author implemented a 1-bit PCM playback system on the ZX Spectrum, which uses cycle counting to generate sound. The system produces poor quality audio due to the limitations of the 1-bit speaker, but it can be used for simple tones and chords.

Replacing a Rust Enum with a 64-Bit Word Made My Interpreter 17% Faster

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The author refactored the Plush language interpreter's Value type to use a low-bit tagging scheme, reducing memory usage by up to 37% in some benchmarks. The new representation is faster than the old one, with every single benchmark ending up faster.

Paramount Caught Using 'Astroturf' Group to Drum Up Fake Support for Merger

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Paramount's $111 billion merger with Warner Brothers is criticized for its negative impact on labor, consumers, and markets. The company has employed astroturf tactics to create a false grassroots movement in support of the deal.

The 92-Year-Old Mathematician and the Teenage Apprentice

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DHS 'Predictive Policing' Unit Is Analyzing Americans' Financial Habits

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Border Patrol's Predictive Intelligence Targeting Teams (PITT) analyze Americans' financial activity and other data to identify potential targets for traffic stops, raising concerns about civil liberties. The program has led to innocent people being pulled over and questioned, sparking calls for greater oversight and accountability.

Getting your hands dirty is good for you

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Touching natural materials like soil and plants can boost skin's microbial diversity, benefiting the immune system. Research suggests that prolonged or frequent contact with nature could significantly change what's happening on our skin and in our bodies.
A mathematician collaborated with a Large Language Model (LLM) to solve the Navier-Stokes problem, but OpenAI claims to have solved it first. The LLM was used to push the collaboration's work from rough forcing to smooth forcing and incompressible Euler equations.

There's a new "Google Jail" for independent wikis

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The author is discussing the challenges of hosting video game wikis on new domains after a Google core update in March 2024, which has made it difficult for these wikis to show up in search results. The author is exploring possible solutions and potential long-term fixes to this issue.

Disappointed Optimists

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The author discusses the "cursed problem" of designers being asked to change people's behavior for profit, and how this conflict can lead to disappointment and burnout. They suggest that designers must decide which promise they can live without in order to find a compromise.

FreeBSD 14.5-Release

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The FreeBSD 14.5-RELEASE is now available for various architectures, including amd64, i386, aarch64, armv7, powerpc and others. It can be installed from bootable ISO images or over the network using USB memory sticks. The release includes bug fixes and updates to externally-maintained software.

Extracting Steering Vectors from J space

https://darshanmakwana412.github.io/assets/images/posts/jlens-steering_image1.png
The user tested using the Jacobian space to derive steering vectors from concept tokens for simple model behaviors like generating all caps or refusing prompts, but found it prone to hallucinations and brittle.

Antiquated HTML Snippets and Artefacts

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The web has undergone numerous changes due to evolving devices, browsers, and personal preferences. Various non-standard HTML tags have been used to adapt websites for different environments and integrations.

Reverse engineering the 2008 LogiCola, a logic drill program

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The author has released an updated version of LogiCola, a logic practice tool, after receiving feedback from users. The new version includes features such as offline mode and improved accessibility for screen readers.

Mistral raises €3B

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Mistral raised €3 billion in a Series D funding round, valuing the company at over €21 billion. The investment will help Mistral expand its frontier research and infrastructure to support mission-critical AI transformation for global enterprises.