Google DeepMind Releases AlphaGenome Atlas

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Scientists have developed the AlphaGenome Atlas, a database predicting effects of single nucleotide variants in the human genome. The Atlas helps researchers quickly prioritize promising research areas by providing an easy-to-use score for coding and non-coding regions.

DaVinci Resolve 21.1

Media

LibreOffice breaks download records after declaring it has no AI features

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LibreOffice 26.8, a free alternative to Microsoft Office, reached a record download of over 1 million times in one week due to its writing system and typography improvements. The Document Foundation clarified that LibreOffice does not include generative AI features due to privacy concerns and principles it has set for itself.

Benchmarking Qwen3.8 27B quantizations: 4-bit holds up, 1-bit collapses

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The author tested various GPU RAM requirements for running Qwen3.8 27B without sacrificing quality, finding that a 24 GB card like RTX 4090 can handle the full BF16 model with some context reduction.

Why I'm Not Excited About the Graphene OS and Motorola Partnership

https://podcast.switchedtolinux.com/media/podcasts/tehankorage/why-im-not-excited-about-the-graphene-os-and-motorola-partnership_medium.webp
GrapheneOS partners with Motorola for custom Android phones, but the author is cautious. Switched To Linux is a podcast supporting Linux learning and provides convenience posts.

The Helicopter with Radioactive Blades

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The CH-53 Sea Stallion helicopter uses a simple mechanical system to detect rotor blade cracks, involving ionizing radiation from Strontium-90. This method has been effective for decades and is still used today in newer models with fiber optic sensors.

Show HN: Copperhead – Hardware as Fast as Software

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Copperhead is an open-source AI platform for designing and verifying printed circuit boards. It helps hardware teams by automating the design process, ensuring consistency and accuracy.

The two Christian saints who are the Buddha

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The story of saints Barlaam and Josaphat originated from an Arabic version of the Buddhist tale, with similarities to the life of Gautama Buddha, and was later adopted by Christian churches. The shared themes across different faiths highlight a common human experience that transcends individual eras and places.

ZX Spectrum: Experimenting with 1-Bit Sound

The author implemented a 1-bit PCM playback system on the ZX Spectrum, which uses cycle counting to generate sound. The system produces poor quality audio due to the limitations of the 1-bit speaker, but it can be used for simple tones and chords.

How Climate Resilient Are the Largest Cities?

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The report analyzes 72 cities' climate risk and resilience using AlphaGeo's Climate Risk & Resilience Index (CRRI), revealing that European, African, and Latin American cities are more resilient than South Asian megacities.

Disappointed Optimists

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The author discusses the "cursed problem" of designers being asked to change people's behavior for profit, and how this conflict can lead to disappointment and burnout. They suggest that designers must decide which promise they can live without in order to find a compromise.

C*: Unifying Programming and Verification in C

https://arxiv.org/static/browse/0.3.4/images/arxiv-logo-fb.png
Researchers focus on formal verification of systems software due to its safety-critical nature. A new language, C*, integrates proof capabilities into C programming, enabling real-time verification and unifying implementation and proof code development.

AlphaGenome Atlas predictive map of every DNA letter change in the human genome

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Google has introduced AlphaGenome Atlas, a platform predicting the molecular impact of every possible single-letter DNA variant in the human genome. This comprehensive catalogue will help accelerate our understanding of biology and treat disease by providing researchers with an intuitive and free-to-use website portal.

DHS 'Predictive Policing' Unit Is Analyzing Americans' Financial Habits

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Border Patrol's Predictive Intelligence Targeting Teams (PITT) analyze Americans' financial activity and other data to identify potential targets for traffic stops, raising concerns about civil liberties. The program has led to innocent people being pulled over and questioned, sparking calls for greater oversight and accountability.

Paramount Caught Using 'Astroturf' Group to Drum Up Fake Support for Merger

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Paramount's $111 billion merger with Warner Brothers is criticized for its negative impact on labor, consumers, and markets. The company has employed astroturf tactics to create a false grassroots movement in support of the deal.

US police fear Meta smart glasses could be used to secretly record them

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Law enforcement agencies across the US are concerned about Meta's camera-equipped smart glasses being used to secretly record them or aid in terrorism, prompting memos from departments in Maine to California. The technology has raised fears of surveillance and impunity among police and public alike.

Among European Companies That Use a CDN, Nearly 9 in 10 Use Cloudflare

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Cloudflare is the majority front door for 89.6% of European companies with a CDN, while Amazon comes second at 3,112 distinct companies.

Antiquated HTML Snippets and Artefacts

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The web has undergone numerous changes due to evolving devices, browsers, and personal preferences. Various non-standard HTML tags have been used to adapt websites for different environments and integrations.

Extracting Steering Vectors from J space

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The user tested using the Jacobian space to derive steering vectors from concept tokens for simple model behaviors like generating all caps or refusing prompts, but found it prone to hallucinations and brittle.

Reverse engineering the 2008 LogiCola, a logic drill program

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The author has released an updated version of LogiCola, a logic practice tool, after receiving feedback from users. The new version includes features such as offline mode and improved accessibility for screen readers.

There's a new "Google Jail" for independent wikis

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The author is discussing the challenges of hosting video game wikis on new domains after a Google core update in March 2024, which has made it difficult for these wikis to show up in search results. The author is exploring possible solutions and potential long-term fixes to this issue.

I've factored the RSA keys of a Certificate Authority from the 90s

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The author explores the security of RSA cryptography, noting that small keys can be factored on a modest desktop computer and some old root certificates are still vulnerable.

The 92-Year-Old Mathematician and the Teenage Apprentice

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Young Americans have never witnessed a functioning foreign policy

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LG TVs caught spying even when offline or on standby

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LG smart TVs secretly log and upload data about owners even when offline, including location and Wi-Fi network details. This practice is part of Automatic Content Recognition (ACR) technology used by many smart TV manufacturers to identify what users watch.

Mistral raises €3B

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Mistral raised €3 billion in a Series D funding round, valuing the company at over €21 billion. The investment will help Mistral expand its frontier research and infrastructure to support mission-critical AI transformation for global enterprises.

Picolibrary: A Small Press

The author has successfully republished a book, "Professor Mmaa's Lecture", after inquiring about the rights and obtaining a new contract. The process involved scanning the original 1953 edition, OCRing the text with LLMs, and formatting for ebook publication.

Ask HN: Are others seeing Google's reCAPTCHA rejecting Firefox users?

User is experiencing an infinite Google reCAPTCHA loop while accessing archive.is in Firefox on Linux, despite disabling Privacy Badger and trying private browsing. The issue may be related to a configuration problem or a change made by archive.is.

FreeBSD 14.5-Release

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The FreeBSD 14.5-RELEASE is now available for various architectures, including amd64, i386, aarch64, armv7, powerpc and others. It can be installed from bootable ISO images or over the network using USB memory sticks. The release includes bug fixes and updates to externally-maintained software.

End-to-end infrastructure for training and inferencing open weight models

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AC2 is a researcher cockpit for model development and learning, with options to use coding agents or follow the Quickstart. It includes an OpenTelemetry-based observability SDK called ac2.tracing for capturing timing and other metrics.